Before you make any drastic changes, first get to the root of the problem. Why is your job causing so much mental anguish? If it’s your boss, figure out a way to work peacefully together. If it’s the workload, develop ways to work more efficiently (basically smarter, not harder). Before you can begin making changes, you must figure out what the issues are and what needs to be changed. And be realistic, if your long commute, working forty hours or not being able to have brunch with friends is what’s bothering you. You could be suffering from another disease called laziness.